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Biopython is a bioinformatics library for Python providing tools to parse, manipulate, and analyze biological sequences, molecular structures, and phylogenetic trees. It serves as a biological sequence parser for genomic and proteomic data across multiple industry-standard file formats and acts as an interface for querying biological data and citations from NCBI Entrez repositories. The project distinguishes itself through specialized toolkits for protein structure analysis and phylogenetic tree construction. It includes a protein structure analyzer for processing PDB and mmCIF files to calcu
evo2 is a genomic large language model and foundation model designed to predict, generate, and analyze genetic information across different species. It functions as a nucleotide sequence modeler and a DNA sequence generator, using transformer-based sequence modeling to process genomic data. The system provides capabilities for synthetic DNA generation, creating new genetic sequences based on biological prompts or species-specific tags. It also performs nucleotide likelihood prediction to score genomic variants and analyze biological properties within DNA sequences. The model supports genomic
ADAM is a genomics analysis platform with specialized file formats built using Apache Avro, Apache Spark, and Apache Parquet. Apache 2 licensed.
Scalable gVCF merging and joint variant calling for population sequencing projects
Cloud-native genomic dataframes and batch computing
The main features of hail-is/hail are: Domain Specific Processing, Genomic Data Analysis.
Open-source alternatives to hail-is/hail include: biopython/biopython — Biopython is a bioinformatics library for Python providing tools to parse, manipulate, and analyze biological… arcinstitute/evo2 — evo2 is a genomic large language model and foundation model designed to predict, generate, and analyze genetic… bigdatagenomics/adam — ADAM is a genomics analysis platform with specialized file formats built using Apache Avro, Apache Spark, and Apache… dnanexus-rnd/glnexus — Scalable gVCF merging and joint variant calling for population sequencing projects. graphframes/graphframes. apache/incubator-sedona — | Status | Stable | Latest | Source code|Spark compatibility| |:----------:|:-------------:|:------|:------:|:------|…