This repository provides the implementation code for our ICML paper. Below provides an illustration of the sampling process.
Feynman-Kac guided protein design using RFdiffusion. This package implements particle filtering to optimize design objectives during the diffusion process.
B. Ni, D.L. Kaplan, M.J. Buehler, ForceGen: End-to-end de novo protein generation based on nonlinear mechanical unfolding responses using a language diffusion model. Sci. Adv. 10, eadl4000 (2024). DOI: 10.1126/sciadv.adl4000
This repository contains the source code accompanying the paper: